Top 10 Infectious Disease Billing Companies in New York

A patient with a chronic bone infection might need a hospital consult, outpatient follow-ups for months, culture and drug-level labs, IV antimicrobial therapy and a telehealth check-in. Each step carries its own documentation, and each payer may read the policy differently. When notes don’t support the E/M level or an authorization is missed, claims are denied and payment slips. This guide covers the top 10 infectious disease billing companies in New York and nearby remote options, separates documented specialty experience from general billing capability, and explains what to verify before outsourcing. A knowledgeable billing partner matters because small errors repeat across longitudinal care.
Disclosure Sirius Solutions Global publishes this guide and is one of the 10 companies. This is an editorial comparison, not an independently verified ranking. Details come from each company’s public website or published sources. |
In this guide: Comparison · Profiles · Sirius · Challenges · Revenue leaks · Assessment · In-house vs. outsourced · Checklist · FAQ
Key takeaway 1 Only some companies document infectious disease pages; others are general RCM firms. | Key takeaway 2 Documentation, medical necessity and authorization drive payment and denials. | Key takeaway 3 New York Medicaid plans and commercial payers each have their own rules. |

Medicare conversion factor: 2026 final vs 2027 proposed.
Company Profiles
1. MedCloudMD
Overview and services: National RCM firm whose infectious disease page describes custom superbills and billing for testing and treatment, including Lyme disease, malaria and meningitis. Consider it if: you want documented specialty focus. Verify: Who will code your account, and do they know New York payers? Website: medcloudmd.com
2. MedCare MSO
Overview and services: Billing company with an infectious disease page covering coding, claim denials and collections, from scheduling through follow-up. Consider it if: you want specialty content and end-to-end billing. Verify: Ask for evidence behind any revenue-increase claims on its site. Website: medcaremso.com
3. RCM Matter
Overview and services: Offers tailored infectious disease billing and says it serves providers in all 50 states, with routine billing audits and claim tracking. Consider it if: you want a multi-state vendor with audits. Verify: How does it handle New York Medicaid plans? Website: rcmmatter.com
4. TRCB
Overview and services: Virtual RCM partner for infectious disease practices nationwide: billing, coding, old A/R recovery, credentialing and denial management. Consider it if: you have aged A/R to clean up. Verify: Its site cites performance figures; ask for documentation, and how percentage pricing is defined. Website: trcb.com
5. Allzone Management Services
Overview and services: Lists certified coders for infectious disease CPT, ICD-10 and HCPCS coding, plus customized reporting. Consider it if: coding detail is your priority. Verify: New York payer experience is not stated; ask for it. Website: allzonems.com
6. Portiva
Overview and services: Its infectious disease page discusses long-term care, specialized tests and repeated follow-up visits as billing challenges. Consider it if: you want a vendor that frames the specialty’s workflow. Verify: Confirm New York coverage and who handles denials. Website: portiva.com
7. SunKnowledge
Overview and services: New York City-headquartered RCM company offering medical billing across 40+ specialties, prior authorization, A/R collections and virtual assistants. Consider it if: you want a New York-based general RCM partner. Verify: Infectious disease experience isn’t documented; ask for references. Website: sunknowledge.com
8. Medical Billers and Coders (MBC)
Overview and services: Large billing network with a New York page addressing Medicaid managed care, commercial payers and OMIG audit exposure. Consider it if: you bill across many New York payers. Verify: Infectious disease experience isn’t documented; verify any performance figures. Website: medicalbillersandcoders.com
9. Medwave
Overview and services: Billing, credentialing and payer contracting firm with pages for New York City and Albany. Consider it if: you need credentialing and contracting alongside billing. Verify: Ask whether infectious disease clients are among its practices. Website: medwave.io
10. Sirius Solutions Global
Overview and services: This guide’s publisher, a national general medical billing and RCM company. See the next section. Consider it if: you want RCM with credentialing and audits. Verify: How infectious disease coding would be reviewed. Website: siriussolutionsglobal.com
Sirius Solutions Global: Medical Billing and RCM Support for Infectious Disease Practices
Sirius Solutions Global is a national partner for medical billing and revenue cycle management, pairing AI-assisted technology with human-verified billing support. Services include advanced eligibility verification, medical coding, claims management, denial management, prior authorization, credentialing and re-credentialing, A/R follow-up, medical billing audits, revenue leakage assessments and virtual assistant support.
For infectious disease practices, that means confirming coverage and authorizations before visits, reviewing codes against documentation, scrubbing claims, sorting denials by root cause and working aged A/R consistently. We can support appropriate New York practices remotely. We don’t claim a dedicated infectious disease department, a New York office or infectious disease-specific clients, so ask how your coding and payer requirements would be handled.
Want a closer look at your workflow? Request a billing and RCM review from Sirius Solutions Global. |
Why Infectious Disease Medical Billing Requires Specialized Attention
Area | What to know |
E/M coding | Visits are leveled by medical decision making or time, so notes must show the work, such as drug therapy that needs toxicity monitoring. |
Chronic and complex infections | Long-running care needs consistent documentation of status, plan and monitoring at every encounter. |
Antimicrobials and infusion | Where provided, administration codes (CPT 96360–96379) need documented times, route and drug details, with drug billing reviewed carefully. |
Labs and diagnostics | Send-out tests are billed by the performing lab; in-office testing needs the right CLIA certificate. |
Care settings | Hospital consults, inpatient follow-ups and office visits use different codes and documentation. |
Payer policies | Coverage rules and medical necessity requirements differ by payer. Check current CPT, ICD-10-CM, CMS and payer guidance. |

Where infectious disease revenue can slip.
2026 Medicare snapshot The 2026 Medicare conversion factor is $33.4009 for non-qualifying APM clinicians and $33.5675 for qualifying participants (summary). CMS proposed $32.8409 and $33.1693 for 2027 (AMA); confirm final figures. Medicare telehealth flexibilities run through Dec. 31, 2027 (summary). |
• New York Medicaid: Overseen by the NYS Department of Health. Many members are in managed care plans with separate authorization and appeal processes, and Medicaid providers can be audited, so documentation matters.
• Commercial plans: The Department of Financial Services regulates insured plans, not self-funded employer plans. Confirm which prompt-payment and surprise-billing rules apply.
• Telehealth: New York’s payment parity law was extended through April 1, 2028 for Medicaid and DFS-regulated plans, with limits (budget summary).
Where Infectious Disease Practices May Be Losing Revenue
Revenue leakage area | Common problem | Recommended RCM action |
Eligibility | Incorrect coverage information | Eligibility verification |
Coding | Incorrect code selection | Coding review |
Documentation | Incomplete clinical documentation | Documentation review |
Infusion billing | Missing or inaccurate administration details | Billing and coding validation |
Claims | Submission errors | Claim scrubbing |
Denials | Repeated unresolved denial reasons | Root-cause denial management |
A/R | Delayed follow-up | Structured A/R management |
Underpayments | Reimbursement discrepancies | Payment reconciliation |
Educational only; these steps don’t guarantee recovered revenue.
How Efficient Is Your Infectious Disease Billing Process?
# | Question | Answer |
1 | Do you verify insurance eligibility before appointments? | ☐ Yes ☐ No |
2 | Are coding and documentation reviewed before claim submission? | ☐ Yes ☐ No |
3 | Do you monitor denial trends? | ☐ Yes ☐ No |
4 | Is outstanding A/R reviewed regularly? | ☐ Yes ☐ No |
5 | Do you identify underpayments? | ☐ Yes ☐ No |
6 | Can your team track claim status? | ☐ Yes ☐ No |
7 | Are payer-specific billing requirements reviewed? | ☐ Yes ☐ No |
Yes answers | Result |
0–2 | Your practice may benefit from a billing workflow review. |
3–5 | Several opportunities for RCM improvement may exist. |
6–7 | Continue monitoring performance and maintaining consistent controls. |
Educational self-check, not a financial audit. Request a medical billing and RCM review.
In-House vs. Outsourced Infectious Disease Billing
Factor | In-house billing | Outsourced billing |
Staffing | Internal hiring and training | External billing team |
Technology | Practice-managed systems | Depends on provider |
Coding support | Internal or contracted | Depends on provider |
Denial management | Internal follow-up | Dedicated workflow where offered |
Reporting | Internal tools | Provider’s reporting capabilities |
Scalability | Depends on staffing | Depends on contract and capacity |
Cost structure | Salaries and operating costs | Contract-based pricing |
The right choice depends on practice size, billing complexity, resources and operations.
Questions to Ask Before Hiring a Billing Company
Tick | Question |
☐ | Does the company understand infectious disease billing? |
☐ | Can it support CPT and ICD-10-CM coding workflows? |
☐ | How does it handle infusion-related claims? |
☐ | What is its denial management process? |
☐ | How does it monitor aged A/R? |
☐ | Does it provide regular performance reports? |
☐ | How does it protect patient information? |
☐ | Does it have trained human billing specialists? |
☐ | What billing software and integrations does it support? |
☐ | Are pricing and contract terms transparent? |
Frequently Asked Questions
▸ What does an infectious disease billing company do?
It turns visits, labs and treatments into claims, then handles coding review, submission, denial follow-up, A/R and reporting, often with credentialing.
▸ Why is infectious disease billing complex?
Documentation, medical necessity, lab and infusion rules, authorizations and long-term care add specialty-specific detail.
▸ How much do billing services cost?
Models include percent of collections, flat fee or per claim. We don’t quote prices; request written terms.
▸ What CPT codes are common?
Often office and hospital E/M codes. Depending on services, also infusion and injection codes (96360–96379) and lab codes. Verify with a certified coder.
▸ How can practices reduce denials?
Verify coverage and authorizations early, align notes with codes, scrub claims and track denial causes.
▸ What does infectious disease RCM include?
Eligibility, coding, claims, payment posting, denials, A/R, credentialing and reporting.
▸ Should practices outsource billing?
It depends on volume, staffing and cost. Outsourcing can reduce workload, but you remain responsible for compliance.
▸ How do I choose a company in New York?
Compare documented specialty experience, NY Medicaid and Medicare knowledge, HIPAA safeguards, reporting and references.
▸ Can a company handle infusion billing?
Some can. Ask how administration time and drug details are documented and reviewed.
▸ Does Sirius offer RCM support?
Yes: billing, coding, eligibility, claims and denial management, prior authorization, credentialing, A/R, audits and reporting. We are multi-specialty.
Disclaimer This article is general information, not legal, financial, coding, billing or medical advice. Payer rules, CPT® codes (© AMA) and fee schedules change, so confirm with CMS, NYS agencies, your payers and qualified counsel or certified coders. Company details come from public sources as of November 2026 and are unaudited. Listing is not endorsement or ranking. Sirius Solutions Global is listed and has a financial interest. No result is guaranteed. To request a correction, contact us through our website. |





